Study: Could Microbe Manipulation Offer An Alternative To Weight Loss Surgery?

Obesity is a global health problem, with more than 40% of the American population considered obese according to the Center for Disease Control. Researchers at Arizona State University and elsewhere are researching gut activity in relation to obesity and weight management, and note that some of the trillions of microbes within the gut play a substantial role. These microbes regulate food digestion and subsequently body weight. Learn about this new research here as part of your commitment to fast weight loss education with help from Phentermine 37.5 mg.

More Effective Therapies

The gut can provide the key researchers need to create more effective weight loss therapies. “Temporospatial shifts in the human gut microbiome and metabolome after gastric bypass surgery,” by ASU researcher Zehra Esra Ilhan and ASU Biodesign professor Rosa Krajmalnik-Brown was recently published in npj Biofilms and Microbiomes. They along with researchers from Mayo Clinic and Pacific Northwest National Laboratory are currently researching how the gut changes after gastric bypass surgery.

“Our findings highlight the importance of changes in mucosal and fecal microbiomes that are reflected on gut metabolism after surgery,” said Ilhan. The microbial changes after surgery corresponded to persistent changes in fecal fermentation and bile acid metabolism, both of which are associated with improved metabolic outcomes.”

An End To Invasive Weight Loss Surgery?

While bariatric surgery is considered effective for weight loss, it is also invasive and dangerous. New microbial research could potentially eliminate the need for this type of surgery.

“Previous bariatric surgery-microbiome studies in humans relied largely on fecal samples because sampling through the intestinal mucosal membrane requires an invasive procedure,” said Ilhan.

“Understanding the microbial behavior in the gut could potentially lead to a creating a probiotic that could replace surgery — or an improved indicator to identify the best candidates for surgery and sustained weight loss,” added Krajmalnik-Brown.

Research on this subject is ongoing.
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