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Study: Dopamine & Biological Clock Connected To Overeating & Obesity

A new study from the University of Virginia has found a link between the brain’s biological clock and pleasure center. High-calorie foods, which elicit pleasure center responses in the brain, interfere with regular eating schedules, resulting in overeating. Learn about this study, which was published in the journal Current Biology, to potentially shed light on your Phentermine 37.5mg weight loss regimen. 

A Dramatic Change

Obesity has become a serious problem in the U.S. over the last few decades. 

"The diet in the U.S. and other nations has changed dramatically in the last 50 years or so, with highly processed foods readily and cheaply available at any time of the day or night," Ali Güler, a professor of biology at the University of Virginia, noted. "Many of these foods are high in sugars, carbohydrates and calories, which makes for an unhealthy diet when consumed regularly over many years."

Researchers used mice for their study, with some of the rodents given high-fat foods on a 24/7 basis. “Anytime snacking” was found to cause obesity and related health issues. 

Dopamine Signals Disrupted

The study also found that mice who had their dopamine signals interfered with maintained their normal feeding schedules and did not gain weight. 

"We've shown that dopamine signaling in the brain governs circadian biology and leads to consumption of energy-dense foods between meals and during odd hours," Güler said.

The Modern Human Diet

The caloric intake from the modern diet is mainly to blame for the obesity epidemic.

"The calories of a full meal may now be packed into a small volume, such as a brownie or a super-size soda. It is very easy for people to over-consume calories and gain excessive weight, often resulting in obesity and a lifetime of related health problems,” said Güler. "Half of the diseases that affect humans are worsened by obesity. And this results in the need for more medical care and higher health care costs for individuals, and society."
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