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Sleep Restriction Linked To Fat Metabolism, Study Finds

A new study from the American Society for Biochemistry and Molecular Biology published in Journal of Lipid Research has linked sleep deprivation to feeling less full after fatty meals. Those who go without sufficient sleep for a few days also metabolize food fat differently. Learn about this study as part of your continuing weight management education inspired by Phentermine 37.5mg

A 10-Night Study

Once the 15 healthy men participating in this Pennsylvania State University study enjoyed healthy sleep at home for a week, they checked into a sleep lab for a 10-day study. All the participants were in their 20s. Five of the nights in the sleep clinic required no more than five hours of sleep a night. Kelly Ness, a current postdoctoral fellow at the University of Washington who ran the sleep study, said she and other researchers collected data while also "interacting with the subjects, playing games with them, talking with them -- helping to keep them awake and engaged and positive."

Chili Mac & Sleep Deprivation

To determine how the sleep schedule affected the metabolism, participants were given bowls of chili mac after sleeping poorly for four nights. 

"It was very palatable -- none of our subjects had trouble finishing it -- but very calorically dense," Ness said.

Participants typically felt less satisfied eating the meal compared to when they were well-rested. 

Postprandial Lipid Response

Researchers compared blood samples from the participants, finding that sleep restriction affected the “postprandial lipid response.” Lipids cleared at a faster rate from the blood to increase the chances of weight gain. "The lipids weren't evaporating -- they were being stored," said Orfeu Buxton, a professor at Penn State. "This study's importance relies on its translational relevance. A high-fat meal in the evening, at dinnertime -- and real food, not something infused into the vein? That's a typical exposure. That's very American."

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